I finalized my the TSC’s needed fixes on the website and started working on the policies and procedures manual on security protocols.
I have gone through so much literature that I just want to puke. Just kidding…… but it was a lot though. Who knew it required so much reading right to have a “correct” policies and procedures manual. I’m pretty sure if I had bothered to screen shot how many tabs I had…it would be too much. I’m talking 40+ tabs.
On Thursday, I spent half my time with Jackie lecturing to Poliana and I about the different types of HIV medicines and how they work. We had a real patient come in and she told us to evaluate based on his illnesses and symptoms what type of HIV medicine combination would be best. I definitely thought that was way cool because I got to learn how protease (PR) inhibitors, reverse transcriptase (RT) inhibitors,and nucleotide/nucleoside reverse transcriptase inhibitors (NRTI’s).
Here’s a blurb from http://www.webmd.com/hiv-aids/guide/aids-hiv-medication?page=2
Reverse transcriptase (RT) inhibitors help block an important step in the HIV life cycle. There are two types of RT inhibitors.
Nucleoside/nucleotide reverse transcriptase inhibitors (NRTIs) stall reproduction of HIV. They force the virus to use faulty versions of building blocks.
Non-nucleoside RT inhibitors (NNRTIs) bind to the RT protein. This disables it, keeping HIV from making copies of itself.
I also learned about 3 different type of Hepatitis’ and the differences between them all….for example
Hep A: You usually get hep A from food or water. And you there exists neutralizing antibodies for it so it can go away. One only has a viral load when one is currently sick.
Hep B: Hepatitis B is usually transferred via bodily fluid (i.e. from sexual interactions such as vaginal fluid), blood (needles), mother to child (most often in Asian populations–something I found REALLY surprising), and needle injectors. You can get a vaccine for it to develop antibodies against the virus to neutralize, but you can’t cure it. Usually the antibodies are surface ones and in terms of HIV/AIDS medicine you would use something with tenofovir/lamivudine in it with the HIV medicine.
Often between 10-20 million viral counts means you have it.
Hep C: Hepatitis C is solely from blood and remains largely an occupational health issue because of needle sticks. Anyway that infected flood can go through pores and is from needle sharing and injections. It can affect men and women and people who have hep C remain chronically affected.
Lastly, I learned about ritonavir and it’s awesomeness essentially. So ritonavir is usually used in highly active antiretroviral therapy (HAART)–it’s when you combine a bunch of drugs basically for HIV therapy to treat multiple things. What’s so cool about ritonavir is how just a tiny amount can boost protease inhibitors instead of using as a protease inhibitor by itself (which studies found that many had liver issues when used excessively because of the way ritonavir works— it “inhibits the liver enzyme that normally metabolizes protease inhibitors, cytochrome P450-3A4 (CYP3A4)” .